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2012년 2월 6일 월요일

비타민 D의 주요 사항: The ABCs of Vitamin D

비타민 D는 뼈를 강하게 하는 것으로 알려졌지만 그 외에도 여러 종류의 암, 당뇨병, 그리고 자동면역 장애와 심지어는 체중 증가에도 중요한 역할을 하는 것으로 매우 중요한 비타민이다.
어떤 사람이 결핍이고 안전하고 충분하게 섭취하는 방법에 대해 알아 보자.

Vitamin D Illustration
New Interest in Vitamin D: Most of us know we need vitamin D for strong bones. Now it appears that this nutrient, or rather a lack of it, may play a role in cancer, diabetes, some autoimmune disorders, and even weight gain. See who's at risk for a deficiency and the safest ways to get enough vitamin D.

Normal Spongy Bone Matrix
Vitamin D and Your Bone: Vitamin D allows your body to absorb calcium. Without it, your bones can become brittle and weak. In adults, too little vitamin D can lead to malformed bones and osteoporosis.  In children, vitamin D deficiency once caused many cases of rickets, a bone disease and a major public health problem in the U.S. Fortifying the milk supply with vitamin D virtually eliminated the disorder.
Shown here is a normal spongy bone matrix.

Man Laying on Grass
Vitamin D comes from Sun : In a perfect world, you'd never have to worry about getting enough vitamin D. Your body produces it on its own. The trick is exposing some portion of your skin to direct sunlight for 15 to 30 minutes a few days a week. But the UV rays that stimulate production of vitamin D can also cause skin cancer. So most experts don't recommend getting your vitamin D from sun exposure.

Map of the United States
Vitamin D where you live: The darker a person's skin, the more difficult it is to get vitamin D from  sunlight. Fair-skinned people might be willing to risk the 10 to 15 minutes they need to get enough. But there's still a problem. Unless you live south of a line from Los Angeles to Columbia, S.C., there may not be enough sunlight year round to produce all the vitamin D you need. Some people may need other sources.

Food Sources of Vitamin D
Who's at Risk for "D" Deficiency?Studies find vitamin D deficiency can affect adults, infants, children, and adolescents. Your diet may increase your risk if it's low in milk or the foods that naturally contain vitamin D, such as salmon and eggs. Most people with low blood levels of vitamin D don't notice any symptoms. Others risk factors include:
  • Obesity
  • Digestive disorders like celiac disease
  • Older age (50+)
  • Some medications

Man Running on Nature Trail
Vitamin D and CancerPreliminary research suggests vitamin D may help protect against colon cancer, but its value against breast, prostate, or other cancers is not yet clear.  Better answers may come from the large Vitamin D and Omega-3 Trial (VITAL). In the meantime, experts recommend regular physical activity, a healthy body weight, and a diet high in vegetables, fruits, and whole grains and low in processed and red meat to help prevent cancer.

Depressed Woman Sitting on Bed
Vitamin D and DepressionIt isn't clear how they are related. But studies have linked low levels of vitamin D to depression among older men and women. One possible explanation is that lack of vitamin D causes the parathyroid gland to produce more hormone. Low levels of vitamin D and higher levels of parathyroid hormone have been linked to depression severity.

Smiling Woman Eating Healthy Breakfast
Vitamin D and Weight Gain: After menopause, most women gain weight until they reach their mid 60s. There is evidence, though, that taking a vitamin D and calcium supplement may slow that weight gain. In one study, women who were not getting enough of those two nutrients at the start were 11% less likely to gain weight and more likely to maintain their weight or even lose weight as a result of taking the supplement.


Boy Using Asthma Inhaler
Vitamin D and Children: Evidence shows that children who get adequate vitamin D, either from the sun or from supplements, may have a reduced risk of developing type 1 diabetes. Studies also link inadequate vitamin D to more severe childhood asthma. Children with asthma who have low vitamin D levels have more hospitalizations and use more asthma medications.


Man Eating Healthy Breakfast
Start Your Day with Vitamin DOne way to get vitamin D is through your diet. In the U.S., nearly all milk is fortified with vitamin D, and many brands of orange juice are, too. Even ready-to-eat breakfast cereals can contain a healthy dose. So just by making sure you eat breakfast, you can make every day a "D day."


Salmon and Mushroom Dinner
Vitamin D and DinnerFish — especially fatty fish like salmon, tuna, mackerel, and sardines — are a good source of vitamin D. One 3-ounce portion of cooked salmon can provide nearly 200% of the recommended daily value of vitamin D. Three ounces of specially grown mushrooms that have been exposed to UVB light can provide 100%.


Assortment of Dairy Foods
Eggs, Cheese, and Vitamin DOther food sources of vitamin D include egg yolks, cod liver oil, beef liver, margarine, yogurt, and some cheeses. While milk has been fortified in the United States since the 1930s, the same is not true for all dairy products. Cheese and ice cream may be a tasty source of calcium, but you need to read the nutrition label to know whether or not you're getting vitamin D.


Vitamin D Supplements
Vitamin D SupplementsMost Americans already have enough vitamin D in the bloodstream for good bone health. For those who want or need to boost their intake of vitamin D, supplements are an option. Most multivitamin tablets contain 400 IU of vitamin D. You can also find vitamin D by itself in higher-dose tablets and in combination with calcium.


Vitamin D2 and D3
D2 or D3?, That's the QuestionVitamin D is available in supplements in two forms: D2 and D3. Both forms are effective, and either can be taken to ensure adequate levels of vitamin D. But 2 is not equal to 3. D3 is the kind of vitamin D the body makes, and recent studies suggest that D3 can be up to three times more effective in raising the vitamin D level quickly and staying longer.


Vitamin D Daily Allowances
How Much Vitamin D do You Need?How much vitamin D you need depends on your age and risk factors. The recommended dietary allowance is 600 IU per day for adults up to 70, and 800 IU for ages 71 or older. Some researchers have suggested much larger doses of vitamin D for a variety of health benefits, but too much may harm you. Above 4,000 IU per day, the risk for harm increases, according the Institute of Medicine.


Baby Receiving Oral Medication
Daily Dose for Breastfed Babies: Breast milk provides multiple benefits for babies, but it is not a good source for vitamin D. The American Academy of Pediatrics (AAP) recommends that all breastfed babies receive a 400 IU daily supplement of vitamin D starting shortly after birth and continuing until the baby is weaned and drinking at least 1,000 mL of vitamin D-fortified formula or whole milk. The upper limit is 1,000 IU for babies 0-6 months old and 1,500 IU for babies 6-12 months old.


Close Up of Child Drinking Milk
Vitamin D for Older Children: Children may be able to get the vitamin D they need for growing bones through foods, including those fortified with vitamin D, such as milk.  Beginning at the first birthday, the recommend dietary intake is 600 IU. Supplements are an option to be sure your child gets enough vitamin D, but it's important not go overboard. The upper limits are 2,5 1-3, 3,000 IU for ages 4-8, and from age 9, 4,000 IU.
Hand Removing Blood Sample
Testing for Vitamin DThere is a simple blood test – the 25 hydroxyvitamin D test -- your doctor can order to check your level of vitamin D. Current guidelines indicate that you're getting enough vitamin D to keep your bones healthy when your blood level is 20 nanograms per milliliter (ng/mL) or higher.  Research is ongoing to understand how vitamin D levels in the bloodstream may affect other aspects of health.


Row of Pill Bottles
Vitamin D and Other DrugsSteroid medications can interfere with metabolism of vitamin D. If you take steroids, you should discuss vitamin D with your doctor. The same is true for the weight loss drug orlistat, some cholesterol-lowering drugs, and seizure drugs such as phenobarbitol. Cholesterol-lowering statins, on the other hand, will raise vitamin D levels.


Patient and Doctor Talking
How Much is Too Much?There is an upper limit to how much vitamin D you can safely take. The Institute of Medicine recommendations for adults say that a daily intake of up to 4,000 IU of vitamin D is safe. Taking more than 10,000 IU per day can cause kidney and tissue damage. The best approach is to check with your health care provider before taking vitamin D supplements.

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